TV Cartoon Couples

Tom Petty (Lucky), Kathy N...crap can't spell her name (Peggy), Mike Judge (Hank), and the late Brittany Murphy (Luanne).
Hank and Peggy were married as were Lucky and Luanne on King of the Hill, hince the title of the blog post! (In case you were confused as none of them are married to each other in real life)